About Us

UK Registered Charity: 1211119

The Generation Trust was originally founded in 1983 to support medical research at the Paediatric Research Unit at Guy’s Hospital. We became a Charitable Incorporated Institution (CIO) in 2025. Today, we work closely with the Department of Medical & Molecular Genetics at Kings College London.

We primarily fund pioneering research which has real-world clinical applications, helping to improve genetic diagnosis, carrier screening and potentially therapeutic interventions within the Genomics Medicine Group (GMG).


Our Impact

Supporting Promising Researchers

One of our primary funding priorities is to support promising early career researchers, enabling them to establish themselves and compete for larger grants.  This fills a critical funding gap as less established researchers often struggle to secure financial support for their work in the increasingly competitive funding landscape.

Jake Saklatvala

During my PhD, my research focused on developing computational methods to improve the genetic diagnosis of individuals with rare monogenic diseases. I developed novel approaches to more accurately describe clinical phenotypes and identify causative genes. By transforming free-text clinical descriptions into machine-readable, weighted phenotypic profiles, I demonstrated how “bespoke virtual gene panels” could significantly improve…

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Aminah Ali

During the financial year 2021-22, the Trust completed its support of one PhD student at the Department of Medical and Molecular Genetics at King’s College London, which ended with a short extension to mitigate the effects of the COVID pandemic on research activity and allowed the completion of her thesis. In July 2015 Dr Alan…

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